Experience of using Ecositrin in the treatment of chronic urogenital chlamydia

Experience of using Ecositrin in the treatment of chronic urogenital chlamydia
The results of our own study on the use of Ekozitrin (clarithromycin + lactulose) in the therapy of chronic urogenital chlamydia in 32 patients who had previously received antibiotic therapy for chlamydia with insufficient effect are presented.
Author: A.A. Lavrov, I.M. Korsunskaya
Keywords: #urogenital_chlamydia, #Chlamydia_trachomatis, #prebiotics, #eco_antibiotics, #Ekozitrin

All patients were prescribed complex treatment for 10 days: the antibiotic Ekozitrin at a dose of 500 mg twice daily, immunomodulators, and vitamins. Clinical and etiological cure after one course of therapy was observed in 29 patients (91%). All patients noted good tolerability of the drug and the absence of side effects. Thus, the drug Ekozitrin can be recommended as an effective agent for the treatment of chronic urogenital chlamydia.

Chlamydial Infection Statistics

Urogenital chlamydia is one of the most common sexually transmitted diseases and ranks second in prevalence after trichomoniasis [1, 2].

According to the World Health Organization, over 90 million new cases of chlamydial infection are registered annually worldwide. The high-risk group includes men and women aged 16 to 40. Statistics show that this disease is identified in half of men and one-third of women [3]. Furthermore, about 6–8% of pregnant women suffer from chlamydia.

In 60–70% of cases, intrapartum infection of the fetus occurs – during passage through the infected birth canal during delivery. Chlamydia trachomatis infection is identified in 17% of cases of perinatal fetal death [4]. Urogenital chlamydia is usually asymptomatic.

However, sometimes in women it manifests as cervicitis and is accompanied by mucopurulent vaginal discharge. Visual examination reveals hyperemia and edema of the cervix, erosions around the os, and lymphoid follicles – a specific sign of chlamydial infection. With further progression of the infectious process, salpingitis, salpingo-oophoritis, and endometritis develop, which are characterized by a prolonged, subacute, and oligosymptomatic course [5, 6, 7].

In men, chlamydial infection typically manifests as urethritis and prostatitis. In long-term urogenital chlamydia, 31% of men develop sexual disorders – weakened erection, decreased sexual sensitivity, and premature ejaculation [8].

Опыт применения Экозитринав терапии хроническогоурогенитального хламидиоза

Detailed Description

The full text of the article is available in the file "Experience with Using Ekozitrin in the Therapy of Chronic Urogenital Chlamydia".

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