Amoxicillin Ekobol® tablets 500 mg
Ecoantibiotics are antibacterial drugs manufactured in Russia, available in the most in-demand pharmacotherapeutic classes of antibiotics: aminopenicillins, protected aminopenicillins, macrolides, and fluoroquinolones. They are used for the treatment of infectious and inflammatory diseases of various organs and systems.
Description
Amoxicillin 500 is one of the most popular and effective antibacterial bactericidal drugs. For 46 years, it has been successfully used to treat numerous bacterial infections. The active ingredient irreversibly destroys the cellular structure of harmful bacteria. As a result, the growth of pathogenic microflora slows down, leading to the rapid death of disease-causing microorganisms.
This antibiotic was developed in 1972 by specialists from the British company Beecham. Today, it remains relevant. According to the WHO, amoxicillin is included in the list of drugs that should be used within the healthcare system.
Release Form and Composition
Pharmacies offer amoxicillin in 250 mg and 500 mg tablets and capsules. The oblong tablets are coated with a yellowish-white protective shell. Each tablet has a convenient scoring notch on each side.
The main active ingredient is amoxicillin trihydrate. The auxiliary components include magnesium stearate, povidone, sodium starch glycolate, and microcrystalline cellulose. The film coating consists of titanium dioxide, talc, and hypromellose.
Indications for Use
This broad-spectrum antibiotic helps get rid of various infections that affect different organs and systems. Typically, doctors recommend this drug for the treatment of infectious diseases caused by the development of streptococci. Among the most common diseases of this origin are:
- Infections of the upper respiratory tract and ENT organs (otitis media, sinusitis, tonsillitis, frontal sinusitis);
- Bacterial diseases of the lower respiratory tract (community-acquired pneumonia, acute bronchitis, and chronic bronchitis in an acute stage);
- Kidney and urinary tract diseases (cystitis, pyelonephritis);
- Intestinal infections (enteritis, colitis);
- Infectious lesions of the skin and soft tissues (phlegmon, abscess, erysipelas);
- All indications for use (see full instructions)
In combination with metronidazole, Amoxicillin tablets are effective in the treatment of chronic gastritis, as well as gastric and duodenal ulcers.
According to scientific data, the likelihood of successful treatment of respiratory tract infections with this antibiotic is 90%. The instructions for use of Amoxicillin also indicate conditions for the prophylactic use of the drug. It is prescribed to patients identified as having a high risk of endocarditis. The antibiotic is sometimes part of the medication arsenal of dentists (the bactericidal agent is relevant for prosthetics and tooth extraction).
Dosage and Administration
The optimal therapeutic dose is prescribed by the attending physician. Self-medication is very dangerous, as each infection requires a specific dosage regimen. The maximum daily amount of the drug is 3 g.
The instructions for use of amoxicillin state that adult patients, as well as children over 10 years old and weighing more than 40 kg, can take no more than 250-500 mg at a time. Typically, the antibiotic is taken three times a day with an eight-hour interval. For successful treatment, it is necessary to adhere to the established therapeutic regimen, without lengthening or shortening the interval. This allows maintaining the optimal concentration of the antimicrobial agent in the body.
Young patients aged 5-10 years can be prescribed no more than 250 mg of the drug three times a day; the recommended dose for children aged 2-5 years is 125 mg. For infants, the daily dosage is established according to body weight: at a rate of 20 mg per kilogram. This amount of the drug should be divided into three doses.
The standard course of antibacterial therapy usually does not exceed 5-14 days. In severe cases of the disease, the dose is sometimes increased to 1000 mg.
When taking tablets, you do not need to change your usual diet. Doctors allow taking the antibiotic both before and after meals. It is recommended to take the drug with alkaline mineral water or milk, and a sufficient amount of liquid should be used. It is better to swallow the tablet whole, but in some cases, it can be split or crushed.
Main Advantages of Amoxicillin
Unlike similar drugs, such as ampicillin and benzylpenicillin, Amoxicillin tablets are absorbed into the blood faster. As a result, the required concentration of the active component is achieved in a short period. Patients do not need to take the medicine frequently, which also saves money.
Another beneficial property identified through the use of Amoxicillin is its resistance to gastric juice. This makes the antibiotic well-suited for oral use.
Amoxicillin 500: Instructions for Use for Treatment and Prevention
It is strictly forbidden to determine the dosage for antibiotic treatment on your own. To exclude possible side effects and ensure the effectiveness of treatment, carefully read the instructions for use of Amoxicillin 500 tablets before taking. As a rule, the instructions for Amoxicillin 500 clearly indicate the recommended duration of the course of treatment. If relief does not occur while following all the conditions, it is necessary to consult your doctor to adjust the antibacterial therapy.
It is not recommended to exceed the treatment period set by the manufacturer, according to the instructions for Amoxicillin 500. This is fraught with the development of antibiotic resistance and a decrease in its effectiveness. A repeat course of treatment with Amoxicillin 500, according to the instructions, is possible only after several months. To exclude the likelihood of resistance, the drug should be combined (alternated) with other antibiotic options.
When Should You Not Take the Drug?
The instructions for use of Amoxicillin indicate that it is a relatively safe antibiotic with few contraindications. Nevertheless, it should be completely avoided in case of individual intolerance to the main active ingredient. Increased sensitivity to the components of the drug often manifests as an allergic reaction. The allergy can be relatively safe, like urticaria, but it can also cause Quincke's edema and anaphylactic shock.
According to the instructions for use of Amoxicillin, other contraindications include complex liver and kidney dysfunction, phenylketonuria, and acute lymphoblastic leukemia.
Sometimes, against the background of taking the drug, abdominal pain occurs, frequent urges for defecation bother, watery stool with blood appears, and temperature rises. These symptoms may indicate pseudomembranous colitis. In this case, it is necessary to stop treatment with this antibiotic as soon as possible.
Amoxicillin in tablet form is not prescribed to children under three years of age (it is better to use a suspension). The drug is also not recommended for nursing mothers. The fact is that the drug easily penetrates into breast milk and can provoke allergies and disruption of the intestinal microflora.
Therapy During Pregnancy and Lactation
The instructions for use of amoxicillin 500 do not prohibit treatment with this drug during pregnancy, but extreme caution should be exercised. The antibiotic is allowed for use during pregnancy if the expected benefit to the mother outweighs the potential risk to the fetus. A doctor may prescribe this antibacterial drug if a pregnant woman develops acute sinusitis, tonsillitis, otitis media, bronchitis, or pneumonia. Also among the indications are cystitis and pyelonephritis.
It is highly not recommended to take amoxicillin while breastfeeding.
Amoxicillin: Instructions for Use for Adults
Despite the minimal number of contraindications, the instructions for use of Amoxicillin for adults indicate that this antibiotic should be used with caution. The specific regimen and dosage must be agreed upon with the attending physician. It is not recommended to deviate from the instructions for use of Amoxicillin for adults to avoid the risk of possible complications and side effects.
Overdose Manifestations
Exceeding the maximum daily amount of the drug usually occurs with self-medication. Overdose can also occur in patients with infectious diseases of the liver and kidneys. This is possible if such patients undergo a traditional course of treatment intended for people without nephrological and hepatological pathologies.
In case of overdose, the patient feels abdominal pain, and also experiences nausea and vomiting urges; diarrhea often appears. The patient may have convulsions. Salt crystals are found in the urine.
If an overdose occurs, it is necessary to stop using Amoxicillin and contact emergency medical specialists. In a hospital, detoxification therapy may be carried out. The patient's stomach is lavaged, and they are given activated charcoal and laxatives. In severe cases, hemodialysis is performed.
Interaction with Other Medicines
The instructions for Amoxicillin indicate that it is often used as part of complex therapy. In combination with other medications, it can affect the condition of various organs and systems of the body.
Simultaneous administration of amoxicillin and oral anticoagulants, similar to warfarin, increases the likelihood of bleeding. When the antibiotic is combined with digoxin, an overdose of both medications often occurs.
According to the instructions for Amoxicillin, its combination with other antibiotics (drugs of the tetracycline series, erythromycin, sulfonamide antimicrobial agents) reduces their effectiveness. Synchronous treatment with amoxicillin trihydrate and methotrexate increases the toxicity of the latter. Such therapy seriously impairs kidney health.
The popular bactericidal drug suppresses the effect of oral contraceptives, which can lead to unplanned pregnancy.
It is important to remember that amoxicillin, according to the instructions, is incompatible with alcoholic beverages. The interaction of the antimicrobial agent with alcohol can cause an acute allergic reaction, which may be fatal. The toxic combination of ethyl alcohol and the antibiotic has a destructive effect on the liver and biliary tract. Alcoholic beverages can be consumed no earlier than 10 days after stopping the drug.
Specific Treatment Recommendations
Amoxicillin with clavulanic acid, like other antibiotics, is completely useless for treating infections caused by viruses, not bacteria. Such infections include influenza. If the disease requires long-term therapy, it makes sense to combine amoxicillin with antifungal drugs.
Particular attention should be paid to bactericidal treatment of infections in patients who have ever had bronchial asthma, hay fever, or allergic diathesis. If a doctor has prescribed high-dose therapy, it is necessary to constantly monitor the condition of the liver and kidneys.
If amoxicillin is used as a component of a medication course to eliminate mild diarrhea, it is wise to avoid drugs that weaken intestinal motility. It is better to use products containing kaolin or attapulgite.
Antibiotic treatment should not be stopped even 2-3 days after the symptoms of the infectious lesion disappear.
Storage Conditions and Shelf Life
The drug should be stored in a dry, dark place at a temperature not exceeding +25°C. Exposure to direct sunlight can destroy the main bactericidal component.
The shelf life of amoxicillin is 3 years from the time of manufacture. Do not buy expired medicine. The antibiotic should be purchased only with a doctor's prescription.
For exhaustive information about the drug, read the detailed instructions for amoxicillin 500 that comes with the packaging of this medication. Our material is an accessible description of the main properties of the popular medication and does not replace the full pharmaceutical characteristics.
Pharmacy Dispensing Terms
By prescription.
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